PHLEBOTOMUS PAPATASI ANTIMICROBIAL PEPTIDES IN LARVAE AND FEMALES AND A GUT-SPECIFIC DEFENSIN UPREGULATED BY LEISHMANIA MAJOR INFECTION

Phlebotomus papatasi Antimicrobial Peptides in Larvae and Females and a Gut-Specific Defensin Upregulated by Leishmania major Infection

Phlebotomus papatasi is the vector of Leishmania major, causing cutaneous leishmaniasis in the Old World.We investigated whether P.papatasi immunity genes were expressed toward L.major, commensal gut microbes, or a combination of both.We focused on sand fly transcription factors dorsal and relish and antimicrobial peptides (AMPs) attacin and defens

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